Through GSVA and GSEA enrichment analyses, it was found that there were A large number of differentially expressed pathways between ARCluster A and ARCluster B. Moreover, the results showed that the expression levels of the pathways related to cell adhesion were all reduced in ARCluster B, which was consistent with the phenomenon that malignant tumors with AR were more likely to break down the barriers of ECM and form metastasis. The gene discussed is AR; the disease is cancer.