Given that brown rats exert significant anti-schistosomal activity during the early weeks of primary infection and then rapidly eradicate a second infection (Knopf et al., 1977; Cioli et al., 1978; Sepulveda et al., 2010), we asked whether antibodies to CX/CF had activity against schistosomula in vitro. The gene discussed is CFTR; the disease is infection.