IRF4 and neoplasm: Given the facts that most LBCL, IRF4+ patients are children and young adults with a GCB‐derived tumor, and the probability of IRF4 rearrangement has been reported to decrease significantly with aging,1, 6 one may wonder whether the better outcome of LBCL, IRF4+ is attributable or related to the young age or the molecular changes such as IRF4 rearrangement.