Six factors were found to be significantly different when analyzed by racial and ethnic group: age at presentation (p = 0.0037), histology (p = 0.0446), Intergroup RMS Study (IRS) group (p = 0.0287), tumor invasiveness (p = 0.0347), metastatic disease (p = 0.0101), and FOXO1 fusion partner (PAX3 or PAX7) in fusion positive tumors (p = 0.0131). Here, FOXO1 is linked to metastatic neoplasm.