Among these genes, POMC produces peptides involved in anti-inflammatory actions [7], BANK1 is associated with systemic lupus erythematosus [37], and MAST3 and AHSA2 are associated with IBD [39, 66], corroborating the role of immunity-related genes in shaping gut microbiota. This evidence concerns the gene MAST3 and systemic lupus erythematosus.