IL17A and rheumatoid arthritis: In addition to these documented compounds, we also detected 42 sesquiterpenoids from these 3 species of Artemisia, such as artemisinin, artemisinin A, artemisinin B, artemisinic acid, dihydroartemisinic acid, etc. Previous studies have found that artemisinin compounds such as ATS can inhibit βIL-1, IL-6, IL-17α and other inflammatory cytokines, suggesting that they play the roles of anti-inflammatory, anti-angiogenesis, inhibiting autoimmune arthritis and treating rheumatoid arthritis [30].