Firstly, in the analysis of overall survival (OS), FAM83A (p = 2.06e-07), KRT6A (p = 1.22e-07), and CYP4B1 (p = 6.72e-05) had the most significant effect on the overall survival of patients with lung adenocarcinoma. This evidence concerns the gene CYP4B1 and lung adenocarcinoma.