RBM4 and esophageal squamous cell carcinoma: To directly test the possible involvement of RBM4 in ESCC, we first measured the RNA levels of RBM4 in a panel of ESCC cell lines and found that RBM4 was significantly increased in ESCC cells as compared to normal esophageal epithelial cells (NE2 and NE3) (Supplementary Fig. 1b).