As with iPSMNs, these mostly involved lncRNAs and the fusion with the greatest burden in ALS post-mortem was a gene neighbour fusion between the lncRNA AL353138.1 and PTCHD4 (OR 4.2, 95% CI 2.3-Inf, Fisher’s p 1.1 × 10−5). The gene discussed is PTCHD4; the disease is amyotrophic lateral sclerosis.