FCGR2A and neoplasm: FcγRIIA (CD32a) is a low-affinity single-chain transmembrane receptor for monomeric IgG that is highly expressed in neutrophils (30,000 to 60,000 molecules/cell31), and its ligation induces Fcγ-dependent functions in neutrophils, such as the release of granule contents, Ca2+ mobilization, anti-tumor cytotoxicity, and phagocytosis49.