Incidence rates and incidence rate ratios of acute myocardial infarction, stroke, cardiovascular-related mortality, major adverse cardiovascular event, all-cause mortality, venous thromboembolism, arterial thromboembolism, and cancer in patients with rheumatoid arthritis receiving Janus kinase inhibitors or tumor necrosis factor inhibitors. The gene discussed is TNF; the disease is acute myocardial infarction.