SLC6A3 and alcohol abuse: Both the dopamine transporter gene SLC6A3 (ρ = 0.967), a candidate risk gene for dopamine or other toxins in the dopamine neurons [51,52] and aldehyde dehydrogenase-1 (ALDH1A1, ρ = 0.949), whose polymorphisms are implicated in alcohol use disorders, map to module M12 (ρ = 0.949) [53].