For instance, while the RTEL1 locus (20q13.33: rs117238689, rs115610405, rs35640778, and rs35902944) harboured variants associated with both LTL and lung adenocarcinoma (Figure 3—figure supplement 1), these signals appeared to be distinct and independent of each other (avg_PP3=0.999, avg_PP4=0.001; Figure 3A, supplementary file 1h). The gene discussed is RTEL1; the disease is lung adenocarcinoma.