The positively correlated genes (CALHM5, CALD1, FERMT2, LATS2, NRP2, KIRREL1, and LAMA4) were expressed less in breast cancer in than normal tissue (Fig. 7E, p < 0.05), while the converse was true for some of the negatively correlated genes (NDUFA7, MIR200CHG, NDUFA3, CNPY2, MCRIP2, METTL26, TECRP1) (Fig. 7E, p < 0.05). The gene discussed is CALD1; the disease is breast cancer.