Secondly, the proportion of bladder and upper tract carcinomas because there is evidence that patients with UTUC have lower PD-L1 expression than those with bladder urothelial carcinoma and they both exhibit significant differences in the prevalence of genomic landscape and carcinogenesis (Yang et al. 2021). The gene discussed is CD274; the disease is renal pelvis/ureter urothelial carcinoma.