Namely, the clinical relevance of ABCB1 expression is diminished or completely lost among young adult AML patients, and particularly in pediatric AML patients.45,51,52,53 In our study median age of AM-NK patients was 51 years, and 61% of older patients (> 51 years) were ABCB1high. This evidence concerns the gene ABCB1 and acute myeloid leukemia.