Aberrant expression of genes that control apoptosis, like BCL2-familly members, represent a recurrent feature of leukemic cells that can lead to increased cell survival and chemotherapy resistance.11,33,34 In this study we analyzed the expression pattern of two BCL2-family member genes, BCL2 and BAX, as well as BAX/BCL2 ratio in order to elucidate their influence on prognosis of AML-NK patients. This evidence concerns the gene BCL2 and acute myeloid leukemia.