Positively related pathways include antigen processing and presentation (down-regulation), chronic myeloid leukemia (CML, down-regulation), cytokine-cytokine receptor interaction (up-regulation), cytosolic DNA sensing pathway (up-regulation), Leishmania infection, PPAR signaling pathway, primary immunodeficiency (down-regulation) and progesterone mediated oocyte maturation. This evidence concerns the gene PPARA and inborn error of immunity.