CD8A and neoplasm: Each bout of exercise evokes a catecholamine dependent mobilization and redistribution of effector lymphocytes (e.g. Natural Killer-cells, γδ T-cells, CD8+ T-cells) that has been purported to improve long-term immunosurveillance by increasing recognition and destruction of premalignant cells in the initial stages of tumor development, and contributing to the suppression of tumor growth (6, 7).