Asiatic acid prevents CP-AKI by anti-inflammatory mechanisms, which may be associated with the inhibition of the expression of pro-inflammatory cytokine IL-1β, TNF-α, monocyte chemotactic protein-1 (MCP-1), caspase-1, and NF-κB activation (Yang et al., 2018). This evidence concerns the gene NFKB1 and acute kidney injury.