The main pathways involved in cancer (hsa05200), fluid shear stress and atherosclerosis (hsa05418), lipids and atherosclerosis (hsa05417), the AGE-RAGE signaling pathway in diabetic complications (hsa04933), and prostate cancer (hsa05215), along with the top 10 pathways along with the targets associated with them (Figure 5E). The gene discussed is RENBP; the disease is cancer.