However, in multivariable regression analysis, only BlaZ and HlgB were positively associated with hemoptysis while HlgC was negatively associated with hemoptysis (Figure 5B); only HlgB, Nuc, and Tsst-1 were positively associated with leukopenia while BlaI and HlgC were negatively associated with leukopenia (Figure 6B); and only PVL remained associated with death in a dose-dependent manner (odds ratio 1.28 95% CI 1.02 to 1.60; Figure 7B). This evidence concerns the gene NUCB1 and Decreased total leukocyte count.