Also in a count of 606 MDD patients, an increase in peripheral blood C-reactive protein (CRP) was found, with approximately 47% of patients having high CRP levels (≥ 3.0 mg/L) and roughly 29% of patients having higher CRP levels (≥ 5.0 mg/L) (Rethorst et al., 2014). The gene discussed is CRP; the disease is major depressive disorder.