While STING, cGAS and IFI16 inhibit murine norovirus (MNV) replication in murine macrophages, STING also interacts with mouse RIG-I and inhibit its downstream signalling, suggesting that STING may exhibit both antiviral and proviral functions during Caliciviridae infections in mice (Yu et al., 2021). This evidence concerns the gene STING1 and Caliciviridae infectious disease.