Beside its physiological relevance, furin isalso involved in the development of various inflammatory diseases,cancers, viral and bacterial infections, atherosclerosis, and neurodegenerativedisorders.3,6 Regarding viruses, furin induces infectionthrough processing of their surface glycoproteins (e.g., S-protein).Furin-mediated cleavage has been reported for glycoproteins producedby numerous evolutionarily diverse viruses, e.g., HIV, influenza,dengue, Ebola, or Marburg.3,7 Thus, furin is regardedas a potential drug target in various viral diseases. The gene discussed is FURIN; the disease is bacterial infectious disease.