IL6 and tuberculosis: To compare the effectiveness of HupB-induced IL-6 release assay and ESAT-6 and CFP-10-medicated IGRA for TB diagnosis, another 89 clinical samples were collected from Wuhan Jinyintan Hospital, Xiangyang city hospital for tuberculosis and Xiangyang Central Hospital, 28 smear-positive PTB patients, 25 of smear-negative PTB patients and 36 HC volunteers.