BRCA2 and ovarian carcinoma: Several genes have been associated with increased risk of ovarian cancer, including BRCA1 and BRCA2 [6], PALB2, BRIP1 [7], RAD51C and RAD51D [8], with the largest percentage of cases (10-15%) being attributable to germline pathogenic variants in BRCA1 or BRCA2 [9].