Finally, the ‘other’ category provided informative evidence towards variant pathogenicity for both BRCA1 (LR: 3.62 (95% CI: 2.61–5.03), supporting evidence) and BRCA2 (LR: 3.46 (95% CI: 2.20–5.43), supporting evidence), if tumours were undifferentiated or poorly differentiated. Here, BRCA2 is linked to neoplasm.