The histopathological hallmark of a number of neurodegenerative disorders, such as Alzheimer’s disease (AD), Pick’s disease, frontotemporal dementia with parkinsonism-17, and progressive supranuclear palsy, is the presence of fibrillar aggregates of tau protein in brain (1, 2, 3, 4, 5, 6, 7, 8). This evidence concerns the gene MAPT and Alzheimer disease.