It was shown that cytoplasmic estrogen receptor (ER)-α, cytoplasmic ER-β, and total progesterone receptor (PR) expression were higher in squamous cell carcinoma than in adenocarcinoma (AD), while HER2 expression was higher in adenocarcinoma than in squamous cell carcinoma (41). The gene discussed is ERBB2; the disease is squamous cell carcinoma.