As such, the aim of this study was to determine the relationship of hand grip strength and TUG performance (and their changes over 5‐years) with long‐term risk for a late‐life dementia event (comprising any dementia‐related hospitalization or death) in community‐dwelling older women (>70 years) and whether any associations provided independent information to APOEƐ4 genotype. This evidence concerns the gene APOE and dementia.