PDCD6IP and colorectal carcinoma: The video of the NTA is shown in Additional File 5 Moreover, as shown in Fig. 5c, all sEV samples obtained from the plasma of both CRC patients (P1-5) and healthy subjects (HS1-5) were characterized for the presence of EV markers (CD81 and Alix) and for the absence of proteins expected to be underrepresented in EVs (Calnexin and Cytochrome C).