Furthermore, experiments using the bING1-239 peptide showed that s-ING1-Ab levels were significantly elevated in sera from patients with CRC, whereas these levels were not significantly higher in sera from patients with other cancers (EC, GC, BrC, and PC) than in those from HDs (Fig. 4A, Additional file 1: Table S3). This evidence concerns the gene ING1 and colorectal carcinoma.