Baculoviral IAP repeat-containing protein 3 (BIRC3) and Tumor necrosis factor receptor (TNFR) associated factor 1 (TRAF1) are highly expressed in NK cells, and their expressions are correlated with NKp30C level [140], suggesting that BIRC3 and TRAF1 are involved in the regulation of NK cell activity in GIST. This evidence concerns the gene TRAF1 and gastrointestinal stromal tumor.