G antigen (GAGE) [171], melanoma-associated antigen (MAGE)-A1 [168, 169], MAGE-A3 [168, 169], MAGE-A4 [168, 169], MAGE-C1 [168, 169], MAGE-C2 (CT10) [171] and New York esophageal squamous cell carcinoma-1 (NY-ESO-1) [168, 169] are present in 12%, 9%-14.3%, 8%-14.3%, 13%-14.3%, 15%-25.8%, 10% and 12%-20.0% of GIST patients, respectively. The gene discussed is MAGEC2; the disease is esophageal squamous cell carcinoma.