In contrast, reference NT-proBNP values were significantly higher than NT-proBNP values of infants with BPD (p = 0.021) and higher than NT-proBNP values of infants with isolated presence of BPD (n = 4, median: 568, IQR: 316–661, p = .009). This evidence concerns the gene NPPB and bronchopulmonary dysplasia.