These data indicate that while tumor-specific T cell numbers are higher in the tumor, there remains a circulating population of memory phenotype tumor-specific T cells in mice bearing PK51940 tumors derived from Pdx-Cre+/− Kras(G12D)+/− Trp53(R172H)+/− Luciferase-SIY+ mice. The gene discussed is KRAS; the disease is neoplasm.