ITGAE and neoplasm: We found that anti-CD25 treatment prior to implantation did not impact the initial peripheral blood SIY-specific T cell response to tumor implantation (Supplementary Fig. S5), and while it decreased the proportion of T regulatory cells in the tumor, it did not impact the accumulation of SIY-specific T cells in the tumor or the proportion of these cells that express CD103 (Supplementary Fig. S5).