For separating DLBCL patients from healthy controls in the DLBCL dataset (GSE32018), TOP2A (AUC: 0.935), DEPDC1 (AUC: 0.935), NEIL3 (AUC: 0.922), and NEK2 (AUC: 0.916) showed good diagnostic performance (Fig. 9B). Here, TOP2A is linked to diffuse large B-cell lymphoma.