MFN2 and Parkinson disease: We, therefore, evaluated MFN2 protein levels upon induction of mitochondrial depolarization with CCCP in hiPSC-derived neurons (Fig. 6a), which were revealed to be significantly higher in the homozygous PRKN-PD line and the heterozygous variant carrier lines, compared to the controls (90.2 ± 8.4 vs. 69.14 ± 8.4 vs. 41.9 ± 8.4; p = 0.016, p = 0.0007, respectively) (Fig. 6b), while there was no difference at basal conditions (data not shown).