CD40 and breast cancer: An analysis of publicly available data sets of bulk gene expression data has shown that splice variants of CD40 are associated with outcomes in TNBC patients;37 however, there are limited data on CD40 protein expression in TNBC tumoral tissue, with one study reporting that cytoplasmic immunohistochemical staining of CD40 in breast cancer (not TNBC specifically) was associated with outcome38.