Likewise, two other p63-related syndromes, the ankyloblepharon‐ectodermal defects‐cleft lip/palate (AEC) syndrome (OMIM: 106260) and Rapp‐Hodgkin syndrome (RHS; OMIM: 129400), can be combined to one entity, AEC/RHS with mutations residing in the α-C-terminus [7, 8]. This evidence concerns the gene TP63 and leukocyte adhesion deficiency type II.