TP63 and split hand-foot malformation: Mutations in TP63 (Bernardini et al., 2008; Duijf et al., 2003; Roberts & Tabin, 1994; Wang et al., 2014) and WNT10B (Bui et al., 1997) have been associated with ectrodactyly, and other regions of the genome have been mapped as containing some still unidentified causal genes.