Two other mutations have been reported at the same codon – the SHFM4 mutation 1 bp upstream (rs121908839, c.955C > T, p.Arg319Cys) (van Bokhoven et al., 2001) and a case report of EEC/LM/ADULT in a Chinese family (c.956G > A, p.(Arg319His) (Otsuki et al., 2020) changing the same nucleotide base as our R319L mutation). Here, TP63 is linked to exstrophy-epispadias complex.