PTEN and neoplasm: While only 5 and 25% of the DLP glands had a normal architecture in vehicle‐treated castrated and PX‐478‐treated sham‐operated Pten(i)pe−/− mice, respectively, > 50% of the glands were tumor‐free in PX‐478‐treated castrated Pten(i)pe−/− mice (Fig 4F and G).