TMTC3 and breast cancer: In the beginning, we measured TMTC3 expression in BC cells after the cells were cultured in the media supplemented with glycose or 2-deoxyglucose, and it was found that the expression of TMTC3 was repressed following the supplementation of glycose, whereas 2-deoxyglucose supplementation elevated TMTC3 expression in BC cells (Figure 2a, p < 0.01).