No evident effect on the lactic acid concentration in BC cells was displayed in BC cells following the transfection of TMTC3 overexpression plasmid (Figure 4b), whereas it was clear that TMTC3 overexpression decreased the viability and colony formation yet enhanced the apoptosis of BC cells cultured with glycose (Figure 4c–e, p < 0.01). Here, TMTC3 is linked to breast cancer.