To validate the effect of Bor on the induction of MM cells apoptosis, Bax, Bcl-2, cleaved-caspase 3, cleaved poly (ADP-ribose) polymerase-1 (PARP-1), and γH2AX levels were analyzed by Western blotting (Fig. 3). The gene discussed is PARP1; the disease is Miyoshi myopathy.