And it was reported that lncRNA ZNFX1 antisense RNA 1 (ZFAS1) could regulate the autophagy level of NPC cells through the miR-100/autophagy related 10 (ATG10) axis and the PI3K/AKT/mTOR pathway to affect tumor progression [127]. The gene discussed is PIK3CA; the disease is nasopharyngeal carcinoma.