PIK3CA and nasopharyngeal carcinoma: Additionally, it was shown that family with sequence similarity 225 member A (FAM225A) was an oncogenic lncRNA that promotes NPC cell proliferation, migration, and invasion via the FAM225A-miR-590-3p/miR-1275/integrin subunit beta 3 (ITGB3)/focal adhesion kinase (FAK)/PI3K/AKT signaling pathway.