For example, Guang et al. [44] found that the functional delivery of endothelial progenitor cell-derived extracellular vesicles to lncRNA TUG1 could improve sepsis induced by bacterial outer membrane vesicles by endowing anti-inflammatory macrophages with polarization by impeding miR-9-5p targeting SIRT1 inhibition. The gene discussed is TUG1; the disease is Sepsis.