GSTM1 and acute coronary syndrome: Later, in 2015, the National Institute for Health and Care Excellence (NICE) guideline10 reinforced the concept of keeping the Hb transfusion threshold at 80 g/L for patients with ongoing acute coronary syndrome, and at 70 g/L for all the other cases, in the absence of a major hemorrhage, while in 2016 the Swiss Society of General Internal Medicine (SSGIM) released a recommendation11, similar to that of ASH.