PROS1 and hyperinsulinemic hypoglycemia, familial, 4: Clinicians should consider coronary artery embolism in patients with MI and risk factors for thromboembolism, especially atrial fibrillation, prosthetic valves, atrial septal defect, left-sided valvular disease (infectious endocarditis, aortic or mitral calcification), intracardiac tumors, and thrombophilia (factor V Leiden, protein C and protein S deficiency, factor XII deficiency, malignancy, systemic lupus erythematous) [51, 52].