In 8/56 (14.3%) cases, PD-L1 + TILMs were noted in < 10% of the examined optical fields, and in 9/56 (16.1%) PD-L1 covered > 10% of optical fields; Fig. 1B. Expression of PD-L1 in cancer cells was directly related to PD-L1 expression in TILMs (p < 0.05). This evidence concerns the gene CD274 and cancer.