While the need for such a drug lead was highlighted over a decade ago receiving over 600 citations,<sup>1</sup> to date, no such drugs are available.<sup>2</sup> Here, we report the development of a novel ACE2 stimulator, designated '2A'(international PCT filed), which is a 10 amino acid peptide derived from a snake venom, and demonstrate its in vitro and in vivo efficacy against SARs-CoV2 infection and associated lung inflammation. This evidence concerns the gene ACE2 and severe acute respiratory syndrome.