We found that when comparing the minoritized group to the non-Hispanic White group, the mediating effect of CRP on incident dementia accounted for 3% (95% CI: 0%, 6%) of the disparity, and the proportion due to interaction accounted for 14% (95% CI: 2%, 25%) (Supplemental Table 6 & Supplemental Fig. 3). The gene discussed is CRP; the disease is dementia.