In our fully adjusted regression-based mediation models, the decomposition analysis comparing minoritized versus non-minoritized groups showed that the mediating effect of CRP accounted for 2% (95% CI: 0%, 6%) of the disparity in incident dementia, while the interaction effect between minoritized group status and elevated CRP accounted for 12% (95% CI: 2%, 22%) of the disparity (Table 3 & Supplemental Fig. 2). This evidence concerns the gene CRP and dementia.