FMR1 and Anxiety: Results of the behavioral characterization of Fmr1-KO mice in the open field and EPM test indicate hyperactivity as well as lower anxiety in this mouse model consistent with previous reports performed in 2−5 months old Fmr1-KO mice using the same tests (Mineur et al., 2002; Qin et al., 2002; Saré et al., 2016).